| File Format | cineSync for OS X | cineSync for Windows |
| 3GPP | Yes | Yes |
| 3GPP2 | Yes | Yes |
| GIF | Yes | Yes |
| AVI | Yes# | No |
| BMP | Yes | Yes |
| DV | Yes | Yes |
| FLC | Yes | Yes |
| JPEG | Yes | Yes |
| SWF | Yes | No |
| ASF | Yes | No |
| MQV | Yes | Yes |
| Yes | No | |
| PSD | Yes | Yes |
| PCS | Yes | Yes |
| PCT | Yes | Yes |
| PNG | Yes | Yes |
| Quartz Composer Composition | Yes | No |
| QIF | Yes | Yes |
| QT | Yes | Yes |
| MOV | Yes | Yes |
| SDV | Yes | Yes |
| SGI | Yes | Yes |
| Targa | Yes | Yes |
| TIFF | Yes | Yes |
| VDU | Yes | Yes |
| WMV | Yes* | No |
| EXR | Yes^ | Yes |
| DPX | Yes^ | Yes |
| CIN | Yes^ | Yes |
* - In order to view WMVs you must download the Windows Media® Components for QuickTime.
# - In order to view AVIs you must download the DivX Codec for QuickTime.
^ - Single frame support only, not continuous frame sequence playback.